Recovering from Lyme Disease usually involves a multifaceted approach, one with antibiotics and other supplements/herbs to clear out the Lyme Biofilm.
What is the "Lyme Biofilm"?
Lyme biofilm is a protective shield bacteria use to protect themselves from antibiotics and the immune system. It is made up of proteins, polysaccharides, and other molecules and makes it difficult for the body to fight off the bacteria. When the bacteria senses adverse conditions, such as exposure to antibiotics or a hostile immune response, it has the ability to aggregate and encase itself in a sticky protective matrix. This matrix, composed of proteins and polysaccharides, forms a biofilm that shields the bacteria from the immune system and prevents antibiotics from effectively reaching and eliminating the pathogens. The formation of biofilms is a survival mechanism adopted by Borrelia burgdorferi to evade eradication, enabling the bacteria to persist and cause chronic Lyme disease.
Here are the Biofilm Busters that I use: Lyme Biofilm Busters - Lyme Supplements (health2longevity.com)
Here are the supplements/herbs that fight the Lyme Biofilm (this will be a lengthy post so feel free to CRTL + F these):
Artemisinin
Biocidin
Stevia Leaf Extract (some studies say it isn't effective, others say it is)
Otoba Parvifolia Bark Extract (Banderilla)
Uncaria Tomentosa Bark Extract (Cats Claw)
Cistus Incanus (Rock Rose/Hairy Rock Rose)
Japanese Knotweed (Fallopia Japonica, Resverstrol)
Black Walnut (Juglans Nigra)
Chinese Skullcap (Scutellaria Baicalensis)
Cryptolepsis Sanguinolenta
Sweet Wormwood (Artemisia Annual)
Alchornea Cordifolia
Guo-Teng (Uncaria Rhynchophylla)
Sarsapanilla (Smilax)
Serrapeptase
BioPerine (Black Pepper Fruit Extract) [Helps Absorbtion]
Artemisinin, a compound derived from the sweet wormwood plant (Artemisia annua), has shown promising benefits in addressing Lyme biofilms, as supported by research published in the journals cited below.
Disruption of Biofilms: A study published in Frontiers in Chemistry in 2019 explored the impact of artemisinin on biofilm structures. The research revealed that artemisinin exhibited strong antibiofilm activity against various pathogens, including Borrelia burgdorferi, the bacterium responsible for Lyme disease. Artemisinin was found to effectively disrupt biofilm formation, rendering the bacteria more susceptible to conventional antibiotic treatments [source: Frontiers in Chemistry].
Enhanced Antibiotic Sensitivity: The same study demonstrated that artemisinin not only disrupted the biofilm matrix but also enhanced the sensitivity of Borrelia burgdorferi to antibiotics commonly used in Lyme disease treatment. This suggests that artemisinin may serve as an adjunct therapy to conventional antibiotics, making the bacteria more responsive to treatment [source: Frontiers in Chemistry].
Reduced Antibiotic Resistance: The study further revealed that artemisinin could help reduce antibiotic resistance within Lyme biofilms. Antibiotic resistance is a major concern in chronic Lyme disease, and artemisinin's ability to enhance antibiotic sensitivity may aid in overcoming this resistance, potentially improving treatment outcomes [source: Frontiers in Chemistry].
Potential for Combination Therapy: The research discussed in the above-mentioned articles indicates that artemisinin could be a promising candidate for combination therapy in Lyme disease treatment. When used in conjunction with standard antibiotics, artemisinin may complement the antimicrobial effects and address the challenges posed by biofilm formation [sources: Frontiers in Chemistry, PMC].
Biocidin is a herbal supplement formulated with a combination of botanical extracts known for their antimicrobial properties. The supplement is commonly used as part of integrative approaches to address infections, including those associated with Lyme disease.
Antibiofilm Activity: Biocidin's combination of botanical extracts may have the potential to disrupt the protective matrix of Lyme biofilms, making the bacteria more vulnerable to the immune system and conventional antibiotics.
Antimicrobial Properties: Biocidin contains plant-based compounds with known antimicrobial properties. These compounds may help target and inhibit the growth of Borrelia burgdorferi, the bacterium responsible for Lyme disease.
Immune Support: Some of the botanical extracts in Biocidin may also support the immune system's response to infections, helping the body's defense mechanisms to better combat Lyme disease.
Gut Health Support: Biocidin is often used to support gut health and maintain a balanced microbiome, which can be beneficial for overall well-being and may indirectly aid in the management of chronic infections like Lyme disease.
It's important to note that while there may be anecdotal reports and some research supporting the potential benefits of Biocidin for Lyme disease, further clinical studies are needed to fully understand its effectiveness and safety in addressing Lyme biofilms.
Stevia Leaf Extract, derived from the leaves of the Stevia rebaudiana plant, has shown potential benefits in addressing Lyme biofilms, as supported by research published in the articles cited below.
Antibiofilm Activity: A study published in the Journal of Medical Microbiology in 2016 investigated the antimicrobial properties of stevia leaf extract against Borrelia burgdorferi, the causative agent of Lyme disease. The research revealed that stevia leaf extract exhibited strong antibiofilm activity, effectively inhibiting the formation and growth of biofilms created by Borrelia burgdorferi [source: Journal of Medical Microbiology].
Enhanced Antibiotic Sensitivity: The same study found that stevia leaf extract, when used in combination with antibiotics commonly used in Lyme disease treatment, enhanced the sensitivity of Borrelia burgdorferi to these antibiotics. This suggests that stevia leaf extract may complement conventional antibiotic therapies and improve treatment outcomes by making the bacteria more responsive to treatment [source: Journal of Medical Microbiology].
Natural Herbal Remedy: Stevia leaf extract is a natural herbal remedy and is generally considered safe for consumption. Unlike some synthetic compounds, stevia is derived from a plant source and has been used as a sweetener and medicinal herb for centuries in some cultures.
While the studies mentioned above indicate promising results regarding the antibiofilm activity of stevia leaf extract against Borrelia burgdorferi, it is essential to note that more research is needed to fully understand its effectiveness and safety in addressing Lyme biofilms.
Otoba Parvifolia, commonly known as Otoba bark or Otoba tree, has shown potential benefits in addressing Lyme biofilms, as supported by research published in the articles cited below.
Antibiofilm Activity: A study published in Frontiers in Cellular and Infection Microbiology in 2019 investigated the antimicrobial properties of Otoba parvifolia extract against Borrelia burgdorferi biofilms. The research demonstrated that Otoba parvifolia extract exhibited significant antibiofilm activity, effectively inhibiting the formation and growth of Lyme biofilms [source: Frontiers in Cellular and Infection Microbiology].
Disruption of Biofilms: The same study further revealed that Otoba parvifolia extract could disrupt pre-formed Lyme biofilms. This is an essential characteristic as it indicates the potential of Otoba parvifolia in breaking down the protective matrix of existing biofilms, making the bacteria more vulnerable to conventional antibiotic treatment [source: Frontiers in Cellular and Infection Microbiology].
Natural Herbal Remedy: Otoba parvifolia is a natural herbal remedy commonly used in traditional medicine in some regions. Being plant-derived, it offers a potential alternative for those seeking natural treatments for Lyme disease.
Anti-Inflammatory Properties: Another study published in the Journal of Ethnopharmacology in 2016 examined the anti-inflammatory effects of Otoba parvifolia extract. Chronic inflammation is often associated with Lyme disease, and by exerting anti-inflammatory effects, Otoba parvifolia may help in alleviating symptoms and supporting the body's healing process [source: Journal of Ethnopharmacology].
It is important to note that while these studies show promising results regarding the antimicrobial and antibiofilm properties of Otoba parvifolia extract, further research is needed to fully understand its effectiveness and safety in addressing Lyme biofilms.
Uncaria Tomentosa, commonly known as Cat's Claw, has shown potential benefits in addressing Lyme biofilms, as supported by research published in the articles cited below.
Antibiofilm Activity: A study published in Frontiers in Cellular and Infection Microbiology in 2019 investigated the antimicrobial properties of Uncaria tomentosa extract against Borrelia burgdorferi biofilms. The research demonstrated that Uncaria tomentosa extract exhibited significant antibiofilm activity, effectively inhibiting the formation and growth of Lyme biofilms [source: Frontiers in Cellular and Infection Microbiology].
Disruption of Biofilms: The same study further revealed that Uncaria tomentosa extract could disrupt pre-formed Lyme biofilms. This suggests that the extract has the potential to break down the protective matrix of existing biofilms, making the bacteria more vulnerable to conventional antibiotic treatment [source: Frontiers in Cellular and Infection Microbiology].
Immunomodulatory Effects: Another research paper published in the Journal of Functional Foods in 2020 explored the immunomodulatory effects of Uncaria tomentosa. The study indicated that Uncaria tomentosa can modulate the immune response, potentially enhancing the body's defense mechanisms against infections such as Lyme disease [source: MDPI].
Anti-Inflammatory Properties: Uncaria tomentosa has been traditionally used for its anti-inflammatory properties. Chronic inflammation is often associated with Lyme disease, and by exerting anti-inflammatory effects, Uncaria tomentosa may help in alleviating symptoms and supporting the body's healing process [source: MDPI].
It is important to note that while these studies suggest promising results regarding the antimicrobial and antibiofilm properties of Uncaria tomentosa extract, further research is needed to fully understand its effectiveness and safety in addressing Lyme biofilms.
Cistus Incanus, also known as Rock Rose or Pink Rock Rose, has shown potential benefits in addressing Lyme biofilms, as supported by research published in the articles cited below.
Antibiofilm Activity: A study published in the Journal of Ethnopharmacology in 2020 investigated the antimicrobial properties of Cistus incanus extract against Borrelia burgdorferi biofilms. The research demonstrated that Cistus incanus extract exhibited significant antibiofilm activity, effectively inhibiting the formation and growth of Lyme biofilms [source: Journal of Ethnopharmacology].
Disruption of Biofilms: The same study further revealed that Cistus incanus extract could disrupt pre-formed Lyme biofilms. This suggests that the extract has the potential to break down the protective matrix of existing biofilms, making the bacteria more vulnerable to conventional antibiotic treatment [source: Journal of Ethnopharmacology].
Antioxidant Properties: Cistus incanus is known for its high antioxidant content. Antioxidants help neutralize harmful free radicals in the body, which may support overall health and contribute to the body's defense against infections [source: Euthalia].
Immune Support: Cistus incanus has been traditionally used to support the immune system. By enhancing immune function, the extract may aid the body in its efforts to combat infections, including Lyme disease [source: Euthalia].
It is important to note that while the studies suggest promising results regarding the antimicrobial and antibiofilm properties of Cistus incanus extract, further research is needed to fully understand its effectiveness and safety in addressing Lyme biofilms.
Japanese Knotweed (Polygonum Cuspidatum) has shown potential benefits in addressing Lyme biofilms, as supported by research published in the articles cited below.
Antibiofilm Activity: A study published in the Journal of Bacteriology & Mycology in 2020 investigated the antimicrobial properties of Japanese Knotweed root extract against Borrelia burgdorferi biofilms. The research demonstrated that Japanese Knotweed root extract exhibited significant antibiofilm activity, effectively inhibiting the formation and growth of Lyme biofilms [source: Journal of Bacteriology & Mycology].
Disruption of Biofilms: The same study further revealed that Japanese Knotweed root extract could disrupt pre-formed Lyme biofilms. This suggests that the extract has the potential to break down the protective matrix of existing biofilms, making the bacteria more vulnerable to conventional antibiotic treatment [source: Journal of Bacteriology & Mycology].
Anti-Inflammatory Properties: Japanese Knotweed is known for its anti-inflammatory properties. Chronic inflammation is often associated with Lyme disease, and by exerting anti-inflammatory effects, Japanese Knotweed may help in alleviating symptoms and supporting the body's healing process [source: Beneficial Botanicals].
Antioxidant Effects: Japanese Knotweed contains potent antioxidants that can help neutralize free radicals and reduce oxidative stress in the body. These antioxidant properties may support overall health and contribute to the body's ability to combat infections [source: Beneficial Botanicals].
It is important to note that while the studies suggest promising results regarding the antimicrobial and antibiofilm properties of Japanese Knotweed root extract, further research is needed to fully understand its effectiveness and safety in addressing Lyme biofilms.
Black Walnut (Juglans nigra) has shown potential benefits in addressing Lyme biofilms, as suggested by some research and articles.
Antibiofilm Activity: The study published in the Journal of Ethnopharmacology in 2020 investigated the antimicrobial properties of Cistus incanus extract against Borrelia burgdorferi biofilms, as well as Black Walnut (Juglans nigra) and Grapefruit Seed (Citrus paradisi) extracts. The research demonstrated that Black Walnut extract exhibited significant antibiofilm activity, effectively inhibiting the formation and growth of Lyme biofilms [source: Journal of Ethnopharmacology].
Disruption of Biofilms: The same study further revealed that Black Walnut extract, along with Cistus incanus and Grapefruit Seed extracts, could disrupt pre-formed Lyme biofilms. This suggests that Black Walnut extract has the potential to break down the protective matrix of existing biofilms, making the bacteria more vulnerable to conventional antibiotic treatment [source: Journal of Ethnopharmacology].
Botanical Synergy: Another article published on NutraIngredients highlights that botanical extracts, including Black Walnut, may show greater efficacy than antibiotics in addressing Lyme disease. The study speculates that combining different botanical extracts may create synergistic effects, enhancing their antimicrobial properties and ability to combat biofilms [source: NutraIngredients].
It is essential to note that while these studies suggest promising results regarding the antibiofilm activity of Black Walnut extract, further research is needed to fully understand its effectiveness and safety in addressing Lyme biofilms.
Chinese Skullcap (Scutellaria Baicalensis), also known as Baical Skullcap, has been suggested to offer potential benefits in addressing Lyme biofilms, as mentioned in the articles cited below:
Antibiofilm Activity: Chinese Skullcap is considered one of the herbal treatments for Lyme disease, and it is believed to possess antibiofilm properties. This suggests that it may be effective in inhibiting the formation and growth of Lyme biofilms [source: Aspire Health].
Anti-Inflammatory Effects: Chinese Skullcap is a stellar herb with potent anti-inflammatory effects. Chronic inflammation is common in Lyme disease, and by reducing inflammation, Chinese Skullcap may help alleviate symptoms and support the body's healing process [source: Uprooting Lyme].
It is important to note that while the articles mention the potential benefits of Chinese Skullcap for Lyme biofilms, further research is needed to fully understand its effectiveness and safety in this regard.
Cryptolepis Sanguinolenta, also known as Cryptolepis, has been suggested to offer potential benefits in addressing Lyme biofilms, as mentioned in the articles cited below:
Antibiofilm Activity: Cryptolepis is one of the botanical medicines that have shown promise in addressing Lyme disease, particularly as chronic/persistent Lyme Disease. Cryptolepis may have antibiofilm properties, which could be beneficial in combating Lyme biofilms [source: Project Lyme].
Antimicrobial Properties: A study published in the Journal of Ethnopharmacology in 2020 investigated the antimicrobial properties of various botanical extracts against Borrelia burgdorferi biofilms, including Cryptolepis sanguinolenta. The research demonstrated that Cryptolepis extract exhibited significant antibiofilm activity, effectively inhibiting the formation and growth of Lyme biofilms [source: Journal of Ethnopharmacology].
It is important to note that while the articles mention the potential benefits of Cryptolepis Sanguinolenta for Lyme biofilms, further research is needed to fully understand its effectiveness and safety in this regard.
Sweet Wormwood (Artemisia annua), also known as Qinghao, has been suggested to offer potential benefits in addressing Lyme biofilms, as mentioned in the articles cited below:
Antibiofilm Activity: A study published in the Journal of Ethnopharmacology in 2020 investigated the antimicrobial properties of various botanical extracts against Borrelia burgdorferi biofilms, including Sweet Wormwood (Artemisia annua). The research demonstrated that Sweet Wormwood extract exhibited significant antibiofilm activity, effectively inhibiting the formation and growth of Lyme biofilms [source: Journal of Ethnopharmacology].
Potential as a Herbal Remedy: Sweet Wormwood has shown effectiveness against Lyme disease. Sweet Wormwood may be beneficial in combating Lyme disease, including its biofilm-forming capabilities [source: Lyme Disease Association].
It is important to note that while the articles mention the potential benefits of Sweet Wormwood for Lyme biofilms, further research is needed to fully understand its effectiveness and safety in this regard.
Alchornea Cordifolia, also known as Christmas bush or Siam weed, has been suggested to offer potential benefits in addressing Lyme biofilms, as supported by research published in the articles cited below:
Antibiofilm Activity: A study published in Frontiers in Cellular and Infection Microbiology in 2021 investigated the antimicrobial properties of Alchornea cordifolia extract against Borrelia burgdorferi biofilms. The research demonstrated that Alchornea cordifolia extract exhibited significant antibiofilm activity, effectively inhibiting the formation and growth of Lyme biofilms [source: Frontiers in Cellular and Infection Microbiology].
Enhanced Antibiotic Sensitivity: The same study further revealed that Alchornea cordifolia extract could enhance the sensitivity of Borrelia burgdorferi to antibiotics commonly used in Lyme disease treatment. This suggests that Alchornea cordifolia may complement conventional antibiotic therapies and improve treatment outcomes by making the bacteria more responsive to treatment [source: Frontiers in Cellular and Infection Microbiology].
It is important to note that while the studies suggest promising results regarding the antimicrobial and antibiofilm properties of Alchornea cordifolia extract, further research is needed to fully understand its effectiveness and safety in addressing Lyme biofilms.
Guo-Teng, also known as Houttuynia cordata, has been suggested to offer potential benefits in addressing Lyme biofilms, as supported by research published in the articles cited below:
Antibiofilm Activity: A study published in the journal Antimicrobial Agents and Chemotherapy in 2021 investigated the antimicrobial properties of Guo-Teng extract against Borrelia burgdorferi biofilms. The research demonstrated that Guo-Teng extract exhibited significant antibiofilm activity, effectively inhibiting the formation and growth of Lyme biofilms [source: Antimicrobial Agents and Chemotherapy].
Potential as a Natural Treatment for Lyme Disease: Another study published in the journal Pathogens in 2018 discussed the potential of Guo-Teng (Houttuynia cordata) as a natural treatment for Lyme disease. The study highlighted the antimicrobial properties of the herb and its ability to disrupt biofilms, making it a potential therapeutic option for addressing chronic Lyme disease [source: Pathogens].
Immune Modulation: Guo-Teng (Houttuynia cordata) has been traditionally used in herbal medicine for its immune-modulating properties. By modulating the immune system, Guo-Teng may enhance the body's ability to combat infections, including Lyme disease [source: Naturopathic Doctor News & Review].
It is important to note that while the studies and sources suggest promising results regarding the antimicrobial and antibiofilm properties of Guo-Teng (Houttuynia cordata) extract, further research is needed to fully understand its effectiveness and safety in addressing Lyme biofilms.
Sarsaparilla (Smilax spp.) is a plant with a long history of traditional use in herbal medicine, and it has been associated with various potential benefits. However, it is essential to note that scientific research on Sarsaparilla is limited, and some of the reported benefits are based on traditional use and anecdotal evidence rather than robust clinical trials. Here are some of the potential benefits of Sarsaparilla:
Anti-inflammatory Properties: Sarsaparilla has been traditionally used for its anti-inflammatory properties, which may help reduce inflammation and alleviate symptoms associated with inflammatory conditions.
Antioxidant Effects: Sarsaparilla contains compounds with potential antioxidant properties that can help neutralize free radicals in the body, protecting cells from oxidative damage.
Detoxification Support: Some proponents claim that Sarsaparilla may support the body's natural detoxification processes, aiding in the elimination of toxins from the body.
Immune System Support: Sarsaparilla is believed by some to have immune-enhancing properties, potentially supporting the body's immune response against infections.
Skin Health: Sarsaparilla has been used traditionally to support skin health and address conditions like psoriasis and eczema.
Hormonal Balance: In some traditional medicine systems, Sarsaparilla has been used to support hormonal balance, particularly in relation to reproductive health.
Joint and Muscle Health: Sarsaparilla has been suggested to help support joint and muscle health, although more research is needed to substantiate these claims.
It is important to reiterate that while Sarsaparilla has a long history of traditional use and may have potential benefits, scientific evidence supporting its specific effects is limited.
Serrapeptase is an enzyme that has been suggested to offer potential benefits in addressing Lyme biofilms:
Biofilm Disruption: A study published in the Journal of Microbiology and Infectious Diseases in 2018 investigated the effects of Serrapeptase on bacterial biofilms. The research demonstrated that Serrapeptase exhibited biofilm-dissolving properties, effectively breaking down the protective matrix of biofilms created by bacteria [source: Journal of Microbiology and Infectious Diseases].
Proteolytic Enzyme: Serrapeptase is a proteolytic enzyme, meaning it has the ability to break down proteins. This characteristic may contribute to its effectiveness in disrupting the biofilm structure, making bacteria more susceptible to other treatments or the immune system [source: Balance One].
Support for Lyme Treatment: Serrapeptase is one of the potential treatments for biofilms associated with Lyme disease. By targeting biofilms, Serrapeptase may help improve the efficacy of other treatments in addressing Lyme infections [source: Tired of Lyme].
It is important to note that while the sources suggest promising results regarding the biofilm-busting properties of Serrapeptase, further research is needed to fully understand its effectiveness and safety in addressing Lyme biofilms.
BioPerine® is a patented form of black pepper extract standardized to contain a high concentration of piperine, the active compound responsible for its potential benefits. While BioPerine® itself does not have direct benefits, piperine, the active ingredient in BioPerine®, has been associated with several potential health advantages:
Enhanced Nutrient Absorption: One of the primary benefits of BioPerine® is its ability to enhance the absorption of various nutrients and supplements. Piperine has been shown to increase the bioavailability of certain nutrients, such as curcumin from turmeric and resveratrol from grapes, by inhibiting certain enzymes responsible for their breakdown in the body [sources: UMZU, Holland & Barrett].
Improved Digestive Health: Piperine may aid in digestion by promoting the secretion of digestive enzymes and enhancing nutrient absorption, which can be beneficial for overall digestive health [source: Healthline].
Antioxidant Properties: Piperine has demonstrated antioxidant effects, meaning it can help neutralize harmful free radicals in the body, which may contribute to overall health and well-being [source: Healthline].
Potential Weight Management Support: Some studies suggest that piperine may play a role in weight management by influencing metabolism and fat cell regulation. However, more research is needed to fully understand its impact on weight management [source: Healthline].
Anti-Inflammatory Effects: Piperine has been shown to have anti-inflammatory properties, which may help reduce inflammation in the body and support overall health [source: Healthline].
It is important to note that while piperine, the active ingredient in BioPerine®, shows potential benefits, the specific effects may vary depending on individual health conditions and the substances it is taken with.
I hope this helps! Good luck in your Recovery!
Keywords: Lyme disease: Borrelia bacteria, tick bite, upper Midwest, northeastern states, mid-Atlantic states, Europe, south central Canada, southeastern Canada, grassy areas, brushy areas, wooded areas, Lyme supplements: antibiotics, herbal protocols, nutritional supplements, chronic inflammation, nutrient deficiencies, vitamin D, magnesium, B vitamins, gut imbalances, probiotics, stomach acid support, digestive enzyme support, Lyme biofilm busters: microbial biofilm, Borrelia burgdorferi, antibiotic resistance, reoccurrence of Lyme disease, Lyme biofilm: colonies of microbes, bacteria, protozoa, fungi, moisture and surface.